Research Article | Volume: 3, Issue: 12, December, 2013

In vitro screening for acetylcholinesterase inhibition of Baliospermum montanum, Humboldtia brunonis Wall. var. raktapushpa and Pittosporum viridulum

Biju John,  Sulaiman CT,  Sadashiva CT,  Satheesh George and VRK Reddy   
Biju John1, Sulaiman CT2, Sadashiva CT2, Satheesh George3 and VRK Reddy1

1Department of Botany, Bharathiyar University, Coimbatore, Tamilnadu, India,

2Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, Kerala, India,

3Department of Botany, CMS College, Kottayam, India.

Open Access   

Published:  Dec 30, 2013

DOI: 10.7324JAPS.2013.31211
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Abstract

Ethanolic extracts of three medicinal plants collected from South India were analyzed for their activity towards acetylcholinestrase (AChE) enzyme. The AChE inhibition was measured spectrophotometrically. All the three species namely, Baliospermum montanum, Humboldtia brunonis Wall. var. raktapushpa and Pittosporum viridulum showed substantial inhibitory activity towards acetylcholinesterase with IC50 values, 137.5µg/ml, 128.7 µg/ml and 105.3µg/ml, respectively.


Keyword:     Baliospermum montanum Humboldtia brunonis Pittosporum viridulumacetylcholinesterase inhibiters.

Citation:

Biju John, Sulaiman C T, Sadashiva C T, Satheesh George and V R K Reddy. In vitro screening for acetylcholinesterase inhibition of Baliospermum montanum, Humboldtia brunonis Wall. var. raktapushpa and Pittosporum viridulum. J App Pharm Sci, 2013; 3 (12): 063-065.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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