Research Article | Volume: 3, Issue: 8, August, 2013

Comparative in vivo evaluation of three types of honey on topical wound healing activity in rabbits

Nagiat T Hwisa Prakash Katakam Babu Rao Chandu Einas Ghafar Abadi and Ebtihal Mosbah Shefha   

Open Access   

Published:  Aug 30, 2013

DOI: 10.7324/JAPS.2013.3824

The present investigation has focused on the comparative evaluation of topical wound healing activity in rabbits using three types of honeys such as Sidr (SDH), Thyme (TYH), Spring (SPH). The activity was compared with commercial wound healing formulations, Mebo (MBC) and Fusidin (FSC) creams. Among the different types of the honey SDH was found to possess higher healing rate of wounds induced either by thermal or chemical methods. Whereas, in thermal induced burns, both TYH and SPH have shown similar wound healing activity but better than that of standard drugs. The activity for thermal and chemical induced burns was found in the order of SDH > TYH/SPH > MBC > control and SDH > TYH > SPH > FSC > control respectively. Among the three tested honeys, the t-test data was compared to those of controls and it was found that there was a significant (p<0.05) reduction in the wound area. It was concluded that honey in general could be employed as natural topical wound healing agent comparable to commercial synthetic analogs tested in the study. Further the present investigation proves that SDH is possessing superior wound healing activity than that of TYH and SPH.

Keyword:     Honey Sidr Thyme Spring wound healing topical.&


Nagiat T Hwisa, Prakash Katakam, Babu Rao Chandu, Einas Ghafar Abadi and Ebtihal Mosbah Shefha., Comparative in vivo evaluation of three types of honey on topical wound healing activity in rabbits. J App Pharm Sci, 2013; 3 (08): 139-143.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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