Journal of Applied Pharmaceutical Science

Research Article | 2024-04-03

Assessments of anti-breast cancer activity and profiling of active compounds using LC-MS/MS from the Indonesian Agelas nakamurai

Tutik Murniasih, Tri Aryono Hadi, Peni Ahmadi, Martha Sari, Bustanussalam Bustanussalam [...]

Research Article | 2024-04-25

Quantification of asciminib by LC-MS/MS method in human plasma: Validation and stability studies

Hema, Naresh Panigrahi

Research Article | 2024-05-17

Simultaneous determination of levothyroxine and its metabolite liothyronine in human serum by using LC-ESI-MS/MS and its bioequivalence application

Kanchan Soni, Gopal Prasad Agrawal

Research Article | 2024-06-08

Triplet analysis: Quantifying ivacaftor, tezacaftor, and elexacaftor in plasma with mass spectrometry

Ravikanth Inturi, Srikanth Inturi, David Raju Medepalli, Venkata Basaveswara Rao Mandava

Research Article | 2024-07-04

Effect of treadmill exercise on the liver, kidney health, and serum IL-10 levels in high-fat diet-induced obese male Wistar rats

Samreen M. Sheik, H. Madhukar Mallya, Deepak Nayak Manel, Karkala Sreedhara Ranganath Pai, Vani Lakshmi Ramesh Iyer [...]

Research Article | 2024-07-11

The development of a GC-FID method for indirect quantification of chloroacetyl chloride, a potential genotoxic impurity, in chlordiazepoxide hydrochloride drug substance

Srinivas Birudukota, Bhaskar Mangalapu, Ramesha Andagar Ramakrishna, Swagata Halder, Venkata Narayana Palakollu [...]

Research Article | 2024-07-31

Cost-effectiveness analysis of several dosage regimens of vancomycin in ventilator-associated pneumonia critically ill patients

Bobby Presley, Steven Victoria Halim, Eko Setiawan

Research Article | 2024-07-31

Research Trend in The Inhibition of Transient Receptor Potential Vanilloid 1 (TRPV1): Bibliometric Analysis and Visualization

Shereen M. Aleidi, Amani A. Harb, Lina A. Dahabiyeh, Montaha AL-Iede, Islam Hamad [...]

Research Article | 2024-07-31

Diterpene alcohol fraction of Cyperus rotundus Linn essential oil regulates Bcl-2 and Bax expression inducing apoptosis on HeLa in vitro and in silico

Susianti Susianti, Yanwirasti Yanwirasti, Eryati Darwin, Jamsari Jamsari, Arif Setiawansyah [...]

Research Article | 2024-08-01

Computational investigation into Parinari curatellifolia flavonoids as lead hepatoprotective therapeutics

Ayodeji Amobonye, Saheed Sabiu, Mary Tolulope Olaleye, Santhosh Pillai

Research Article | 2024-08-01

Fermented calabash fruit-derived choline (Crescentia cujete L.) against artificial-induced ischemic stroke in rat models: Analysis of N/LR, PWR, histopathology, GM-CSF, and VEGF

Yos Adi Prakoso, Jasir Hakim Hidayah, Sitarina Widyarini

Research Article | 2024-08-01

Isolation and establishment of trans-cinnamic acid as a reference standard from Radix Scrophularia buergeriana Miq

Ngan Nguyen Kim Luu, Ngan My Tran, Phuong Thu Tran, Duong Hoang Trinh

Research Article | 2024-08-12

Computational analysis of Salmalia malabarica (Bombax ceiba) for the management of ulcerative colitis

Savita Bhosale, Prashant G. Jadar, Sunil S. Jalalpure, Vishal S. Patil, Kashinath Hiremath [...]

Research Article | 2024-08-12

Integrating ligand and structure-based discovery approaches to unravel potential novel glyoxalase-I inhibitors

Roa’a Bani-Khalaf, Qosay Al-Balas, Soraya Alnabulsi

Research Article | 2024-08-12

Enhanced bioavailability through quality by design optimization of ceritinib nanostructured lipid carriers: Formulation, characterization, and stability evaluation

Kunchithapatham Janakiraman, Katla Venu Madhav, Sunil Kumar Chaitanya Padavala, Naga Haritha Pamujula

Research Article | 2024-08-17

Anticancer activity of liposomal formulation co-encapsulated with coumarin and phenyl butyric acid

Ali Allateef, Naeem Shalan, Zainab Lafi

Research Article | 2024-08-17

Characterization of functional human insulin produced using the Pichia pastoris expression system

Dini Nurdiani, Eko Wahyu Putro, Endah Puji Septisetyani, Nuruliawaty Utami, Hariyatun Hariyatun [...]

Research Article | 2024-08-17

Endophytic fungi from red ginger (Zingiber officinale var. rubrum) as promising source of antimicrobial and cytotoxic secondary metabolites

Ni Putu Ariantari, Ni Putu Eka Leliqia, I Putu Yogi Astara Putra, Nadzifa Nugraheni, Riris Istighfari Jenie [...]

Research Article | 2024-08-17

A sensitive liquid chromatography tandem mass spectrometric method development and validation for ribociclib and its formulation

J. Ramesh, B. Babu, R. Sangamithra, D. Anandha Jothi, S.N. Meyyanathan [...]

Research Article | 2024-08-20

A design of expert-based development and optimization of voriconazole-loaded aspasomal gel for topical delivery

Shubham Bajirao Patil, Panchakshari Dandagi, Sujay Hulyalkar, Rubeen Dadakalandar Nadaf

Research Article | 2024-08-20

Inhibitory effect of ink derived from Indian Loligo duvauceli squid against HIF1α induced angiogenesis

Seyedeh Sara Kamyab, Alpana S. Moghe, Shyam S. Nandi, Sonali A. Sawant

Research Article | 2024-08-20

Anti-oxidative constituents of Musa balbisiana Colla fruit extract and evaluation of hepatoprotective activity in CCl₄-induced hepatotoxicity in Swiss albino mice

Nabanita Baruah, Madhubanti Das, Kandarpa Kumar Saikia, Jogen Chandra Kalita

Research Article | 2024-08-20

Comparison between solvent evaporation and supercritical CO₂technology in taste-masking of Azithromycin bitter-taste using pH-sensitive Eudragit EPO or Eudragit S100 polymers

Hadeia Mashaqbeh, Rana Obaidat, Mo’tasem M. Alsmadi, Tamara Athamneh

Research Article | 2024-08-20

Standardized mixture of Pluchea indica and Sauropus androgynus extract stimulates the gene expression associated with lactogenesis in rats

Eustachia Diajeng Wandansari, Rul Afiyah Syarif, Dian Eurike Septyaningtrias, Setyo Purwono, Eti Nurwening Sholikhah [...]

Research Article | 2024-08-22

Flavonoid compound of red fruit papua and its derivatives against sars-cov-2 mpro: An in silico approach

Agus Dwi Ananto, Harno Dwi Pranowo, Winarto Haryadi, Niko Prasetyo

Research Article | 2024-08-22

Novel nano-cubosomal chlorhexidine for endodontic irrigation: Development, characterization, and performance evaluation against E. faecalis and streptococcal biofilms in human extracted teeth

Sindhu U. Mukthamath, Ruchira Raychaudhuri, Mamatha Ballal, Kalyana C Pentapati, Krishnaraj Somayaji Shirur [...]

Research Article | 2024-09-09

RP-HPLC method for quantification of cefotaxime sodium by using design of experiment, a green analytical approach: Analytical method development, validation, and application

Akhil Nair, H. Raghu Chandrashekhar, Usha Y. Nayak

Research Article | 2024-09-09

Role of alpha-7 nicotinic acetylcholine receptor down-regulation in cyclic nucleotide reduction in memory-related brain regions of Alzheimer’s rats

Sushma Singh, Neetu Agrawal, Ahsas Goyal

Research Article | 2024-09-09

Anti-diabetes and anti-breast cancer of bioactive compounds-enriched fractions isolated from hemp (Cannabis sativa L. subsp.)

Thanakorn Damsud, Apiradee Pothipongsa, Chalermpong Saenjum, Jirapast Sichaem

Research Article | 2024-09-13

Novel bioanalytical LC-MS/MS method for determination of metoprolol in human plasma

Lakshmana Rao Atmakuri, Raveesha Peeriga, Shabana Begum, Narender Gaddamedi, Bhaskar Vallamkonda [...]

Research Article | 2024-09-13

In silico design of sitagliptin bioisosteres as new inhibitors of Mpro SARS-CoV-2

Abelardo Abad-Giron , Lucero Asmad-Cruz, Angella M. Cordova-Muñoz, Cesar D. Gamarra-Sanchez, Carmen R. Silva-Correa [...]

Research Article | 2024-09-13

Chemical composition, antibacterial, anticancer, and anti-a-glucosidase activities of essential oils from Alpinia nelumboides

Van Thi Kieu Tran, Thang Truong Le, Chuong Hoang Nguyen, Thao Nguyen Thi Tran, Viet Hoang [...]

Research Article | 2024-09-13

Angelica keiskei leaves extract attenuates psychosocial stress in overcrowding-subjected rats

Ferbian Milas Siswanto

Research Article | 2024-09-13

Emulsifier ratio and shock treatment effect on the characteristics of eucalyptus–peppermint oil-based mouthwash nanoemulsion

Christina Winarti, Atika Hamaisa, Susi Lesmayati, Misgiyarta Misgiyarta, Gusmaini Gusmaini [...]

Research Article | 2024-09-21

Evaluation of PPAR gamma agonists: A molecular docking and QSAR study of chalcone analog

Ruchita N. Pingale, Kumar Pratyush, Bhaveshwari Wagh, Ankita A. Jain, Raghu Prasad Mailavaram [...]

Research Article | 2024-09-21

Safflower extract (Carthamus tinctorius Linn.) suppresses proinflammatory cytokines level in rheumatoid arthritis mice model stimulated by complete Freund’s adjuvants

Adryan Fristiohady, Taifo Mahmud, Jia Tuan Maming, Arfan Arfan, Asriullah Jabbar [...]

Research Article | 2024-09-21

Chemometric analysis of GC-MS chemical profiles and biological activities of three citrus essential oils in Indonesia

Einstivina Nuryandani , Erliana Novitasari, Muhammad Fatih Abdurrahman, Nurul Habibi, Ardiba Rakhmi Sefrienda [...]

Research Article | 2024-09-21

Patient and healthcare professional perspective on challenges in lipid profile management in dyslipidemia patients: Two separate cross-sectional surveys

Ramesh Bhandari, Madiwalayya Shivakantayya Ganachari

Research Article | 2024-09-24

Prevalence and risk factors of cosmetic-induced adverse events: A systematic review and meta-analysis

Sweta Kumari, Tambe Daniel Atem, Vaibhav Chaudhary, Sanjeev Kumar Sahu, Biplab Pal [...]

Research Article | 2024-10-01

Repurposing of eluxadoline as a SARS-CoV-2 main protease inhibitor: E-Pharmacophore based virtual screening, molecular docking, MM-GBSA calculations, and molecular dynamics simulations studies

Magdi A. Mohamed, Alaa F. Alanazi, Waad A. Alanazi, Tilal Elsaman, Malik S. Mohamed [...]

Research Article | 2024-10-01

Assessment of psychometric properties of patient education tools for oral anticoagulants

Santosha Vooradi, Gabriel Sunil Rodrigues, Tom Devasia, Ganesh Sevagur Kamath, Vilakkathala Rajesh [...]

Research Article | 2024-10-01

Investigation of the antimicrobial efficacy and cytotoxicity of a natural disinfectant Syzygium cumini (L.) skeels leaf extract on vero cell lines

Haorongbam Joldy Devi, Prathiba Gnanasekaran, Yumnam Asha Devi, Durairaj Siva, Jaihitashee Jayashankar [...]

Research Article | 2024-10-10

Impact on post-stroke injury: Co-administration of metformin and CoQ10 in cerebral ischemia injury

Avinash Singh Mandloi, Chanda Malviya, Chandrashekhar D. Upasani, Vipin Dhote, Aman B. Upaganlawar [...]

Review Article | 2024-05-27

Biological activities of Chrysanthemum morifolium and Chrysanthemum indicum: Molecular prospective

Nur Vaizura Mohamad, Che Nur Mazadillina Che Zahari

Review Article | 2024-05-27

Stability-indicating HPLC method optimization using quality by design with design of experiments approach for quantitative estimation of organic related impurities of Doripenem in pharmaceutical formulations

N. V. V. D. Praveen Boppy, Sharath Babu Haridasyam, Niroja Vadagam, Naveen Sara, Karthik Sara [...]