Towards bioprocessing 4.0: Scaling sustainable innovation in the pharmaceutical bioeconomy

David Gómez-Rios, Howard Ramírez-Malule

DOI: 10.7324/JAPS.2025.v15.i12.1EDPages: 001-003

Chemistry, resources, anticancer effects, other pharmacological properties, and clinical trials of oleandrin from Nerium oleander: An overview

Siu Kuin Wong, Hung Tuck Chan, Eric Wei Chiang Chan

DOI: 10.7324/JAPS.2025.257922Pages: 004-012

Substandard and falsified pediatric medicines in low–middle-income countries: A narrative review on impacts and strategies

Shailee Dewan, Pradeep M. Muragundi, Vani Lakshmi Ramesh, Virendra S. Ligade, Dharmagadda Sreedhar, Adithya D. Shetty

DOI: 10.7324/JAPS.2025.246088Pages: 013-024

Triphala, Trikatu, and Benjakul: an evidence-based review of their pharmacology, toxicology, and clinical potential in integrative medicine

Soiphet Net-Anong, Arisara Phuwajaroanpong, Walaiporn Plirat, Atthaphon Konyanee, Prapaporn Chaniad, Chuchard Punsawad

DOI: 10.7324/JAPS.2025.v15.i12.4Pages: 025-039

Towards a drug distributor price reference index: A 2023 survey of pricing discrepancies for region 02 medicines procured from NCR and local distributors, Philippines

Jinky Marie Tuliao Chua, Julius Tamayao Capili, Ma. Angelita Saquing Rabanal, Lily Ann Caldez Mallabo, Jay Emmanuel Laciste Asuncion

DOI: 10.7324/JAPS.2025.v15.i12.5Pages: 040-045

Development and evaluation of a proniosomal gel for palm tocotrienol-rich fraction topical delivery

Tanya Tong-en Fong, Puxvadee Chaiku, Kar Lin Nyam, Chee Chin Chu

DOI: 10.7324/JAPS.2025.v15.i12.6Pages: 046-059

Impact of pharmacist-led interventions on guideline-directed medical therapy optimization in heart failure with reduced ejection fraction patients

Shiau Fenn Choong, Chee Ping Chong

DOI: 10.7324/JAPS.2025.v15.i12.7Pages: 060-069

Fabrication and characterization of chitosan–gelatin–chondroitin sulfate-diclofenac scaffold with cross-linked glutaraldehyde for potential application in osteoarthritis

Wa Ode Nurfinti, Chrismawan Ardianto, Toetik Aryani, Mareta Rindang Andarsari, Anisa Cendekia Muslimah, Ita Pramudia Ananta, Yusuf Alif Pratama, Nour El Huda Abd Rahim, Sakinato Mazidda, Esti Hendradi, Junaidi Khotib, Fani Deapsari, Aniek Setiya Budiatin

DOI: 10.7324/JAPS.2025.v15.i12.8Pages: 070-078

Anti-inflammatory potential of Indonesian marine sponge Theonella sp.: Mechanisms via TNF-α, IL-6, and IL-12 inhibition

Adryan Fristiohady, Idin Sahidin, Taifo Mahmud, La Ode Muh Julian Purnama, Rathapon Asasutjarit, Fadhliyah Malik, Agung W.M. Yodha, Lidya Agriningsih Haruna, Arfan Arfan, Wahyuni Wahyuni

DOI: 10.7324/JAPS.2025.v15.i12.9Pages: 079-092

Evaluation of the herbal formulation HPH-031508PP in mitigating complications associated with dengue in experimental studies

Mohammed Mukhram Azeemuddin, Madan Mittlekoppa Narendra, Onkaramurthy Mallappa, Raghavendra Pralhada Rao, Bindu Indira, Mohamed Rafiq, Hucharayappa Ganesh

DOI: 10.7324/JAPS.2025.227453Pages: 093-103

Histopathological and immunohistochemical evaluation of the impact of coconut shell-derived liquid smoke hydrogel on diabetic wound healing

Masfria Masfria, Henny Lucida, Yusni Atifah, Hafid Syahputra, Emil Salim, Clarissa Henry, Agnes Valencia, Irfan Syafti, Ardiansyah Selian

DOI: 10.7324/JAPS.2025.v15.i12.11Pages: 104-116

Evaluation of Leptospermum petersonii methanol and ethyl acetate crude extracts for antimetastatic and apoptotic effects against pancreatic and prostate cancer cells

Maria Matlou, Mpho Choene, Lesetja Motadi

DOI: 10.7324/JAPS.2025.v15.i12.12Pages: 117-133

In-silico studies of anti-tuberculosis drugs using advanced computational technique: A DFT, molecular docking, and QSAR analysis

Bhavana Panthi, Anwesh Pandey, Indra Sen Ram, Samiyara Begum, Suresh Kumar

DOI: 10.7324/JAPS.2025.v15.i12.13Pages: 134-145

Wound healing potential of Adenium socotranum (Vierh.) leaf extract: Phytochemical profiling and molecular docking analysis

Ibrahim Ali Al-Hakami, Bushra Abdulkarim Moharram, Hassan M. AL-Mahbashi, Tareq Al Maqtari, Wafa M. Al-Madhagi

DOI: 10.7324/JAPS.2025.261427Pages: 146-160

Exploring the market dynamics of complex generics in United States and India

Amatha Sreedevi, Vani Lakshmi Ramesh, Manthan D. Janodia, Praveen Kumar, Virendra S. Ligade

DOI: 10.7324/JAPS.2025.v15.i12.15Pages: 161-172

The crossroads of Amantadine from antiviral to neurotherapeutic: Bibliometric mapping of six decades of therapeutic evolution

Razan Naji, Ibrahim Albokhadaim, Yassir A. Almofti, Mohammed Al-Rasheed, Maryam Mahmoud, Mahmoud Kandeel

DOI: 10.7324/JAPS.2025.v15.i12.16Pages: 173-181

Investigation of extraction conditions for Oroxylum indicum root using ultrasound-assisted extraction and statistical design of experiments

Nanthawat Thongun, Orawan Monthakantirat, Chantana Boonyarat, Charinya Khamphukdee, Yaowared Chulikhit, Supawadee Daodee

DOI: 10.7324/JAPS.2025.v15.i12.17Pages: 182-192

Isolation, identification, and antimicrobial evaluation of bioactive metabolites from Streptomyces geysiriensis against UTI associated bacterial strains

Mohamed A. El-Sakhawy, Amro Hanora, Mahmoud Mohamed Zaky, Abeer Ali El-Sherbiny Ateya, Heba S. Ibrahim, Roaa Amar Abdel Bast

DOI: 10.7324/JAPS.2025.250607Pages: 193-205

In vitro assessment of α-glucosidase inhibitory activity and compound prediction in Phyllanthus niruri from West Java Indonesia

Idah Rosidah, Alfan Danny Arbianto, Firdayani Firdayani, Agus Supriyono, Kurnia Agustini, Ngatinem Ngatinem, Sri Ningsih

DOI: 10.7324/JAPS.2025.v15.i12.19Pages: 206-218

Angiotensin (1–7) attenuates rotenone-induced Parkinsonism via Mas receptor and Nrf2 pathway in rats

Poonam Bhadauriya, Ahsas Goyal, Vibhav Varshney

DOI: 10.7324/JAPS.2025.247748Pages: 219-229

Antioxidation, antiglycation, and cytoprotective potential of various kratom (Mitragyna speciosa) leaf extracts and its major alkaloid, mitragynine

Rinnapat Boonsut, Juraithip Wungsintaweekul, Charoenwong Premprasert, Narumon Sengnon, Ilham Hama, Supattra Limsuwanchote

DOI: 10.7324/JAPS.2025.v15.i12.21Pages: 230-244

Improving rifampicin stability in the presence of modified isoniazid across different pH environment

Sushruta S. Hakkimane, Santosh L. Gaonkar, Vishnu Prasad Shenoy, Bharath Raja Guru

DOI: 10.7324/JAPS.2025.242027Pages: 245-250

Synergistic modification of polyvinyl alcohol and natural phospholipids: Nanoliposomal carrier for Sonneratia caseolaris L. delivery and therapeutic care

Arman Suryani, Hilda Amie Shafira Istiqhfarin, Nurul Hidayah, Narendra Nazzun Nitisara, Andina Melly Aryanti, Raisya Ardana, Erza Ridha Kartika

DOI: 10.7324/JAPS.2025.243159Pages: 251-265

Mitigating cardiotoxicity of Naja naja venom: Evaluation of a multipronged strategy using anti-snake venom and methanolic extract of Andrographis paniculata

Sujatha Prabhu P., Maya Roche, Ashwini Aithal P., Sreedhara Ranganath Pai K., Varun Kumar Singh, Akshatha Ganesh Nayak

DOI: 10.7324/JAPS.2025.266425Pages: 266-275

Corrigendum to “Characterization, in vitro cytotoxic and antibacterial exploitation of green synthesized freshwater cyanobacterial silver nanoparticles”

DOI: 10.7324/JAPS.2020.10911.corrigendumPages: 276-277