Natural products at the crossroads: Emerging paradigms, translational challenges, and future pathways in drug discovery and development

Mahendran Sekar

DOI: 10.7324/JAPS.2026.302055edPages: 001-003

Anticancer phytochemical nanodelivery systems using graphene derivatives: A review

Muhammad Esa, Sunisa Kaewpaiboon, Muhammad Sohail Khan, Teerapol Srichana

DOI: 10.7324/JAPS.2026.293265Pages: 004-038

Oral modified-release dosage forms: A terminological challenge in science and regulatory affairs

Nelson Enrique Macías García, José David Ortega Salgado, Hannat Gisseth Villa Estrada, Indira Beatriz Pájaro Bolívar, Gina Paola Domínguez Moré

DOI: 10.7324/JAPS.2026.282849Pages: 039-054

Precision approaches in breast cancer: Integrating molecular profiling with targeted nanocarrier-based therapeutics

Akash Sharma, Dilip Kumar Arya, Prashant Pandey, Chimpiri Srujani, Paruvathanahalli Siddalingam Rajinikanth

DOI: 10.7324/JAPS.2026.286596Pages: 055-070

Advancing pharmacoepidemiology and pharmacovigilance: A scoping review of challenges, technological innovations, and global strategies for drug safety

Tanguturi Yella Sree Sudha, Raja Babu, K. S. B. S. Krishna Sasanka, Sumit Kumar Mahato, Harminder Singh

DOI: 10.7324/JAPS.2026.293371Pages: 071-082

Potential stability issue of protein and peptide therapeutic with polyvinyl chloride surface materials: A review

Sinta Wahyu Septiani, Abdul Rohman, Marlyn Laksitorini, Teruna Siahaan

DOI: 10.7324/JAPS.2026.243446Pages: 083-096

Thematic evolution and determinants of patient acceptance of generic medicines: A systematic review and bibliometric analysis with special reference to India

Ruchi Saxena, A. Ameer Hussain, Samuel Mores Geddam, Pratibha Gupta

DOI: 10.7324/JAPS.2026.264242Pages: 097-111

Risk of suicidal thoughts and dizziness associated with tirzepatide: A systematic review and meta-analysis

Ranakishor Pelluri, Mohammad Noor Shaik, Shriraam Mahadevan, Bhima Sridevi, Sravani Thommandru, Asmitha Thota, Vara Prasanth Gummalla, Srikanth Kongara, Vanitha Rani Nagasubramanian, Vishwas Hunsur Nagendra, Jayaraman Rajangam, Usha Sree Puneem

DOI: 10.7324/JAPS.2026.284323Pages: 112-121

Comparative efficacy of SGLT2 inhibitors and Obeticholic acid in MAFLD and Fibrosis: A Systematic Review

Thenmozhi Ganesh, Vignesh Subramani, S. Rajesh Kannan, G. Yuvaraj

DOI: 10.7324/JAPS.2026.246617Pages: 122-134

Nano-vaccines in cancer immunotherapy: Advancing precision and potency in the next generation of therapeutics

Ram Ajay Gupta, Soniya Rani, Akash Verma, Mohit Kumar, Prem Shankar Gupta

DOI: 10.7324/JAPS.2026.257890Pages: 135-147

Reducing prescription errors in Mauritius: Evidence synthesis and practice implications

Vasish Madoo, Angeli Tanwee Sophia, Arshad Muhamod Saroar, Shloka Suresh Sahetya, Ebenezer Wiafe, Khayati Moudgil

DOI: 10.7324/JAPS.2026.283306Pages: 148-153

Microbiota liver crosstalk in diabetic liver injury: Mechanistic insights and therapeutic promise of fecal microbiota transplantation

Onkar Bedi, Gulsheen Panesar, Thakur Gurjeet Singh, Shifali Gupta, Moulik Sharma, Nirbhay Singh Antal, Jatin Saini, Shilpa Katwal, Vaibhav Sapra

DOI: 10.7324/JAPS.2026.283981Pages: 154-161

The lapachol derivatives from Tabebuia aurea: distribution and cytotoxic evaluation against human cancer cells

Rahmat Kurniawan, Arif Ashari, Muhammad Yogi Saputra, Indarto, Peni Ahmadi, Tati Suhartati

DOI: 10.7324/JAPS.2026.285870Pages: 162-168

Development of a validated LC-ESI-MS/MS method for the quantification of tucatinib in plasma samples

Sunil Dattatray Pawar, Deepak D. Kayande, Kokila Pawar, Mazahar Farooqui, Anil Shankarwar, Amol Deshpande, Sunil Shankarwar

DOI: 10.7324/JAPS.2025.213916Pages: 169-175

Modulation of inflammatory pathways by Caryota mitis in rheumatoid arthritis: In-vitro and in-vivo insights

Sandesh Kumar Pattanaik, Swagata Pattanaik, Sovan Pattanaik, Sudipta Jena, Diptirani Rath

DOI: 10.7324/JAPS.2026.286618Pages: 176-186

Development of a vaccine-hesitancy prediction instrument: Application of machine learning

Nour Hanah Othman, Irraivan Elamvazuthi, Santhanathan Rajendram, Helvinder Kaur Balbir Singh, Muhammad Hadhrami Mohd Hussain, Mohammed Tahir Ansari, Karna Vishnu Vardhana Reddy

DOI: 10.7324/JAPS.2026.249217Pages: 187-198

Renoprotective effects of Strychnos potatorum seed extract in streptozotocin-induced diabetic nephropathy: Enhancement of antioxidant defenses and Zonula occludens-1 expression

Abarajitha Shankaranarayanan, Manickam Subramanian, Sharmila Aristotle, Sundarapandian Subramanian, Prabhu Kaliyaperumal

DOI: 10.7324/JAPS.2026.295760Pages: 199-211

Neuroprotective effects of magnolol in aluminium chloride and D-galactose induced Alzheimer’s disease model

Abhinav Anand, Navneet Khurana, Neha Sharma, Rajesh Kumar, Daisy Sharma, Neelam Kumari, Bhupendra Singh

DOI: 10.7324/JAPS.2026.289886Pages: 212-225

Protective role of Phyllanthus acidus ethanolic extract in modulating leptin, dyslipidemia, insulin resistance, and oxidative stress in diet-induced obesity: A comparative study with Zingiber aromaticum

Imaniar Ranti, Mae Sri Hartati Wahyuningsih, Emy Huriyati

DOI: 10.7324/JAPS.2026.289621Pages: 226-235

Anxiolytic activity of hydroalcoholic Manilkara zapota (Linn.) leaf extract in Swiss albino mice

Supriya Ajetrao, Shubhangi Sutar, Rachana Bhimanwar, Nilofar Naikwade, Sarang Mahamuni

DOI: 10.7324/JAPS.2026.268861Pages: 236-243

Comparative in-silico docking, pharmacokinetic characterization, and antimicrobial evaluation of 2,4-DTBP and chlorhexidine against gingivitis-associated oral pathogens

Aswathy Venugopal, Sajith Sathyamoorthy, Emilin Renitta, Dilipraj Sathyamurthy, Vivek Keshri, Vinayaka Kanivebagilu Shankaranarayana, Murugan Sevanan

DOI: 10.7324/JAPS.2026.272831Pages: 244-254

Repurposing of spironolactone for hypertension-related fatigue: Experimental evidence from salt-sensitive rats with computational molecular analysis

Muhamad Rizqy Fadhillah, Wawaimuli Arozal, Raymond Rubianto Tjandrawinata, Dewi Sukmawati, Edwina Rugaiah Monayo, Fachrur Rizal Mahendra, Deni Noviana

DOI: 10.7324/JAPS.2026.298305Pages: 255-265

Effectiveness and safety of short-term second-line anti-tuberculosis therapy in patients with multidrug-resistant tuberculosis

Linda Purnamawati Suherman, Muhammad Guntur Kusumadinata, Sri Wahyuningsih, Didi Permana, Faizal Hermanto, Alfi Nurul Islamiyah, Robby Ramdani, Putri Hidayah

DOI: 10.7324/JAPS.2026.301446Pages: 266-277

Development of alginate bead-based three-dimensional culture of hepatocellular carcinoma cells with cytotoxicity assessment of thymoquinone

Abdelkader Hassani, Samir Chadli, Mohamed Atoui, Billel Smili, Hamad Ali Hamad, Zakaria Boual, Abd Almonem Doolaanea

DOI: 10.7324/JAPS.2026.309285Pages: 278-285