Research Article | Volume: 6, Issue: 12, December, 2016

Novel Egyptian bacterial strains exhibiting antimicrobial and antiaflatoxigenic activity

Amal Hathout Aziza El-Nekeety Ahmed Hamed Bassem Sabry Mohamed Abdel-Aziz Mosad Ghareeb Soher Aly   

Open Access   

Published:  Dec 28, 2016

DOI: 10.7324/JAPS.2016.601201
Abstract

The aim of this study was to isolate and characterize new Egyptian marine bacterial strains and to evaluate the antimicrobial, antioxidant and total phenolic content of their bioactive secondary metabolites. Eight bacterial strains were isolated from marine sediment samples collected from different areas in Red sea governorate, Egypt. Antifungal activity was recorded as zone inhibition of growth between the fungus and the organism tested and two bacterial isolates were selected (designated 21 and 30). These isolates significantly reduced fungal growth and AFB1 production especially the isolate 30. These promising isolates were selected and identified using molecular identification technique and identified as Brevundimonas and Bacillus. The crude extracts from the two bacteria were extracted and the biological activity of these crude extracts was studied. The crude extracts exhibited potent antimicrobial activities against a set of microbial pathogens as well as antioxidant activity and total phenolic content.


Keyword:     Alkaliphilic bacteria AFB1 PCR 16S rRNA antimicrobial activity antiaflatoxigenic activity antioxidant capacity total phenolic content


Citation:

Hathout A, El-Nekeety A, Hamed A, Sabry B, Abdel-Aziz M, Ghareeb M, Aly S. Novel Egyptian bacterial strains exhibiting antimicrobial and antiaflatoxigenic activity. J App Pharm Sci, 2016; 6 (12): 001-010.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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